Cannabinoids and systems of the body

Systems of the Body

Excerpts From Scientific References (click excerpt to link to article)

CARDIOVASCULAR SYSTEM

“Since its discovery in the early 1990s, the ECS has increasingly emerged as a key signaling system involved in all physiological and pathological functions in mammals.”

NERVOUS SYSTEM

“Given the broad involvement of the ECS in nervous system development, homeostasis, dysfunction and energy balance, the more we know of the ECS the better are the prospects for capitalizing on endocannabinoid-based therapies in each disease context.”

SKELETAL SYSTEM

“Recent studies suggest an important role for the skeletal endocannabinoid system in the regulation of bone mass in both physiological and pathological conditions.”

DIGESTIVE SYSTEM

“The endocannabinoid system is an important regulatory system in the GI tract, working in the control of both digestion and host defence; the two major functions of the gut.”

LYMPHATIC SYSTEM

“This work demonstrates a major immunological role for an endocannabinoid.”

MUSCULAR SYSTEM

“Our findings contribute to understanding of the role of the endocannabinoid system in skeletal muscle metabolism and muscle oxygen consumption, and also help to explain the effects of the peripheral endocannabinoid system on whole-body energy balance.”

ENDOCRINE SYSTEM

“So far, endogenous cannabinoids have been confirmed to participate in the regulation of food intake and energy homeostasis of the body, and have a significant impact on the endocrine system, including the activity of the pituitary gland, adrenal cortex, thyroid gland, pancreas, and gonads.”

RESPIRATORY SYSTEM

“That the EC system has an important role in the physiological control of respiration by modulating the respiratory rate and consequently influencing arterial oxygen saturation.”

CIRCULATORY SYSTEM

“Preclinical and some clinical studies have suggested that targeting the endocannabinoid system can improve cardiovascular functions in a number of pathophysiological conditions, including hypertension, metabolic syndrome, sepsis, and atherosclerosis.”

INTEGUMENTARY SYSTEM

“It seems that the main physiological function of the cutaneous ECS is to constitutively control the proper and well-balanced proliferation, differentiation and survival, as well as immune competence and/or tolerance, of skin cells. The disruption of this delicate balance might facilitate the development of multiple pathological conditions and diseases of the skin (e.g. acne, seborrhea, allergic dermatitis, itch and pain, psoriasis, hair growth disorders, systemic sclerosis and cancer).”

URINARY SYSTEM

UNKNOWN

MALE REPRODUCTIVE SYSTEM

“The endocannabinoid system (ECS) is an evolutionarily conserved master system deeply involved in the central and local control of reproductive functions in both sexes.”

FEMALE REPRODUCTIVE SYSTEM